Adolescence is a transitional stage of physical and physiological development that generally occurs during the period from puberty to legal adulthood. This is a vital part of life. This is also a very critical period of life. In adolescence girls and boys both are floating in a colorful and fantasy world. So everything seems colorful to them. That's why they may go astray. Adolescence is a time of risk. Unlimited freedom brings disasters for them.They rush to the path of destruction without knowing the consequence. Adolescence is a young person who is developing from a child to an adult. Adolescents are unable to various diseases. They may be addicted to alcohol, cigarettes, and other drugs which main course them deadly diseases. They are also in danger of sexual relationships which wheel lead them to intentional and unintentional injuries, unintended pregnancies, and sexually transmitted infections including the Human Immunodeficiency Virus properly known as HIV. Many of them also face a wide range of adjustment and mental health problems. That is why it is necessary to be very careful about the disease that can be life-threatening. It is essential to teach them that addiction to alcohol, cigarettes, and other drugs may destroy their life. Moreover, they shoot be given religious teaching besides general education about physical relationships. They should be given practical examples of what may happen due to unsafe sexual relationships.